4-(2-Tetrahydropyranyloxy)phenylboronic acid

4-(2-Tetrahydropyranyloxy)phenylboronic acid - Names and Identifiers

Name	4-Hydroxyphenylboronic acid THP ether
Synonyms	AKOS BRN-0040 4-Hydroxyphenylboronic 4-HYDROXYPHENYLBORONIC ACID THP ETHER 4-Hydroxyphenylboronic acid THP ether 4-HYDROXYBENZENEBORONIC ACID THP ETHER 4-(2-Tetrahydropyranyloxy)phenylboronic acid 4-(2-TETRAHYDROPYRANYLOXY)PHENYLBORONIC ACID 4-(TETRAHYDRO-2H-PYRAN-2-YLOXY)PHENYLBORONIC ACID 4-(tetrahydro-2H-pyran-2-yloxy)phenylboronic acid [4-(Tetrahydro-2H-pyran-2-yloxy)phenyl]boronic acid 4-HYDROXYPHENYLBORONIC ACID 2-TETRAHYDROPYRANYL ETHER [4-[tetrahydro-2H-Pyran-2-yl)oxy]phenyl]-boronic acid
CAS	182281-01-2
EINECS	145-852-6
InChI	InChI=1/C11H15BO4/c13-12(14)9-4-6-10(7-5-9)16-11-3-1-2-8-15-11/h4-7,11,13-14H,1-3,8H2

4-(2-Tetrahydropyranyloxy)phenylboronic acid - Physico-chemical Properties

Molecular Formula	C11H15BO4
Molar Mass	222.05
Density	1.21±0.1 g/cm3(Predicted)
Melting Point	117-124 °C
Boling Point	411.3±55.0 °C(Predicted)
Flash Point	202.5°C
Vapor Presure	1.68E-07mmHg at 25°C
Appearance	White-like powder
pKa	8.63±0.16(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.543
MDL	MFCD02183525

4-(2-Tetrahydropyranyloxy)phenylboronic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/38 - Irritating to eyes and skin.
Safety Description	S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing.
HS Code	29329990
Hazard Class	IRRITANT

4-(2-Tetrahydropyranyloxy)phenylboronic acid - Introduction

4-Hydroxyphenylboronic acid THP ether is an organic compound with the chemical formula C12H16BNO3.

Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in ethanol, ketones and organic solvents, insoluble in water
-Melting point: About 150-152 ° C

Use:
- 4-Hydroxyphenylboronic acid THP ether can be used as an intermediate in organic synthesis and is commonly used in the synthesis of pesticides, drugs and organic photoelectric materials.

Method:
The preparation method of-4-Hydroxyphenylboronic acid THP ether is relatively complicated. A commonly used method is to obtain the target product through the reaction of benzylamine and O-chlorophenylboronic acid. For specific steps, reference may be made to relevant organic synthesis literatures or patents.

Safety Information:
- 4-Hydroxyphenylboronic acid THP ether is an organic compound, which generally has certain toxicity and irritation.
-During operation, personal protective equipment such as protective gloves, glasses and protective masks should be worn to avoid direct contact with skin and inhalation of vapors.
-During storage and handling, avoid contact with oxidants, strong acids and other substances to prevent dangerous reactions.
-During use, pay attention to well-ventilated conditions to reduce the accumulation of organic solvent vapor. If an accident occurs, appropriate emergency measures should be taken in time, such as eye washing, skin flushing, etc., and medical assistance should be sought.

Last Update：2024-04-09 02:00:43